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Hypotrichosis
Overview
Autosomal recessive hypotrichosis is a condition that affects hair growth. this condition usually begins in infancy with patients developing sparse hair (hypotrichosis) on the scalp. Hair is coarse, dry, and curled (termed woolly hair). Scalp hair may also be lighter in coloration is fragile. Patients typically cannot grow hair longer than a few itches. Eyebrows, eyelashes, and other typically hairy locations on the body can be affected as well. Prognosis is variable with some patients remaining stable over time and others progressing to total scalp hair loss and decreased body hair.
Symptoms
Diffuse decrease in hair on the scalp and sometimes eyebrows, eyelashes, and other typically hair bearing body locations.
Causes
Autosomal recessive hypotrichosis can be caused by several genetic mutations. These genes normally provide instructions for making proteins that are involved in the growth and maturation of cells within the hair follicles.
Diagnosis
Hypotrichosis is diagnosed based on a medical history and physical examination. A biopsy of the scalp may be performed to rule out other conditions.
Treatment
There is no cure for hypotrichosis. Treatment focuses on managing symptoms and preventing further hair loss. Medications, such as minoxidil, may be prescribed to promote hair growth.